Good news to hear that Dr Mayne is diagnosing and treating patients with Lyme Disease in Australia but also good to see he is trying to raise awareness of the presence of Lyme Disease in Australia.
Dr Mayne is building a very interesting website here
From his website here
The CD57 Test
Critical update 2nd December 2010
We now know we are specifically interested in
CD3- CD57+ NK cells
Please note there are also CD57+ T cells but these are helper cells
Normal CD57 NK cell count is >180
>120 as treatment ends has a good prognosis
20-60 chronic Lyme disease
This data is quoted from the following presentation
LYME DISEASE THE NUTS & BOLTS BY JOSEPH T. BURRASCANO, JR, MD presented July 2010 in DePere, WISCONSIN
CD-57 COUNT (Natural Killer Cells)
• Low counts seen in Chronic Lyme when the infection has been active > 1 year
• Reflects degree of infection
• CAN BE A SCREENING TEST!
• Predicts a relapse if low when antibiotics end
• Must use method of LabCorp (normal is >180)
– 20-60- most common result in chronic patients
– >60- Lyme activity minimal
– >120- Relapse NOT likely after treatment ends
From the ILADS conference 2010 thanks to Scott Forsgren Better Health Blog
Dr. Joe Burrascano shared CD57 suppression may occur in XMRV as well as in Borrelia.
Reposted by Dr Speedy The Niceguidelines blog
The NK cells (NK or Natural Killer Cells). They maintain baseline function unaltered, ie perform their function of cell destruction. Nonetheless there are two abnormalities in patients with CFS / ME: A degree of activation slightly above normal and A marked reduction of CD57 in the 11 patients analyzed, so that could be used as a marker to validate these patients, according to Dr. Blanco.
Interesting to read Dr Cheney's comments on XMRV and Lyme Disease here