Lyme disease: the next decade
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Authors: Raphael B Stricker, Lorraine Johnson
Published Date January 2011 , Volume 2011:4 Pages 1 - 9 DOI 10.2147/IDR.S15653 -->Raphael B Stricker, Lorraine JohnsonInternational Lyme and Associated Diseases Society, Bethesda, MD, USAAbstract:
Although Lyme disease remains a controversial illness, recent events have created an unprecedented opportunity to make progress against this serious tick-borne infection. Evidence presented during the legally mandated review of the restrictive Lyme guidelines of the Infectious Diseases Society of America (IDSA) has confirmed the potential for persistent infection with the Lyme spirochete, Borrelia burgdorferi, as well as the complicating role of tick-borne coinfections such as Babesia, Anaplasma, Ehrlichia, and Bartonella species associated with failure of short-course antibiotic therapy. Furthermore, renewed interest in the role of cell wall-deficient (CWD) forms in chronic bacterial infection and progress in understanding the molecular mechanisms of biofilms has focused attention on these processes in chronic Lyme disease. Recognition of the importance of CWD forms and biofilms in persistent B. burgdorferi infection should stimulate pharmaceutical research into new antimicrobial agents that target these mechanisms of chronic infection with the Lyme spirochete. Concurrent clinical implementation of proteomic screening offers a chance to correct significant deficiencies in Lyme testing. Advances in these areas have the potential to revolutionize the diagnosis and treatment of Lyme disease in the coming decade.Keywords: Lyme disease, Borrelia burgdorferi, L-forms, cysts, biofilms, proteomics
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Dr Bransfield talked at the London ILADS conference June 2010 about the Decade of the Microbe.
The sooner researchers and doctors wake up to this the less patients will suffer from illnesses of 'unknown cause' and start getting treatment for the cause of their illness instead of palliative treatments aimed at just managing the symptoms ie Multiple Sclerosis, Fibromyalgia, Rheumatoid Arthritis, Polymyalgia Rheumatica, Autism and so many more.
I have been busy of late and not getting round to posting partly due to the holiday period but also because I seem to be finding so much of interest on Facebook about ME/CFS developments with XMRV, good news that Dr Sarah Myhill has her licence to practise back and lots of interesting information related to Lyme Disease. Much worthy of posting on my blog but I just haven't had time to do so. Anyone interested can follow the link top right of the blog to read some of the latest information there.