Interview with Prof. Ying Zhang at the NorVect Conference 2015
Published on Sep 29, 2015
Prof Ying Zhang from John Hopkins Bloomberg School of Public Health explains why Lyme disease is so difficult to treat. Having worked with Tuberculosis (TB) for many years, he sees the similarities and differences between these to bacteria. With Tuberculosis it is known that you have to treat with certain drug combinations that kill the growing form and the non-growing form (persisters) and if you treat shorter than 6 months, the patient will get a relapse.
The bacterium that causes Lyme disease is much more advanced than the TB bacterium, and the main reason is that it also takes a persisting form. These persister forms of the Borrelia bacteria cannot be cultured.
The two views – ILADS and IDSA are two different ways of seeing the same disease. Prof. Zhang thinks they are both right. When it comes to acute Lyme disease, IDSA is right. Then you only need shorter courses of treatment. When the disease turns chronic, longer courses of treatment with the right drug combinations are needed (ILADS view).
The full presentation from Dr Zhang is available on the Norvect website from their 2015 conference http://norvect.no/about-norvect/
From Norvect website -
Talk: Borrelia Persister Drugs: Implications for Improved Treatment
http://norvect.no/conference/conference-2015/speakers/
Dr Zhang also presented at a recent conference in Cambridge UK, organised by Lyme Disease Action presentations will be available on their website shortly
It was a wonderful opportunity to hear Dr Zhang present and also to have opportunity to discuss his work.
Dr Zhang told me that he studied at Birmingham University and later in London (I think he said UCL) - somewhat ironic for me in view of our Health Authorities head in the sands denial of chronic Lyme Disease, that this leading researcher in this field of why and how Borrelia persists, was trained at two of our Universities.
I have posted previously about Dr Zhang's work
Prof Ying Zhang from John Hopkins Bloomberg School of Public Health explains why Lyme disease is so difficult to treat. Having worked with Tuberculosis (TB) for many years, he sees the similarities and differences between these to bacteria. With Tuberculosis it is known that you have to treat with certain drug combinations that kill the growing form and the non-growing form (persisters) and if you treat shorter than 6 months, the patient will get a relapse.
The bacterium that causes Lyme disease is much more advanced than the TB bacterium, and the main reason is that it also takes a persisting form. These persister forms of the Borrelia bacteria cannot be cultured.
The two views – ILADS and IDSA are two different ways of seeing the same disease. Prof. Zhang thinks they are both right. When it comes to acute Lyme disease, IDSA is right. Then you only need shorter courses of treatment. When the disease turns chronic, longer courses of treatment with the right drug combinations are needed (ILADS view).
The bacterium that causes Lyme disease is much more advanced than the TB bacterium, and the main reason is that it also takes a persisting form. These persister forms of the Borrelia bacteria cannot be cultured.
The two views – ILADS and IDSA are two different ways of seeing the same disease. Prof. Zhang thinks they are both right. When it comes to acute Lyme disease, IDSA is right. Then you only need shorter courses of treatment. When the disease turns chronic, longer courses of treatment with the right drug combinations are needed (ILADS view).
The full presentation from Dr Zhang is available on the Norvect website from their 2015 conference http://norvect.no/about-norvect/
From Norvect website -
Talk: Borrelia Persister Drugs: Implications for Improved Treatment
http://norvect.no/conference/conference-2015/speakers/
Talk: Borrelia Persister Drugs: Implications for Improved Treatment
http://norvect.no/conference/conference-2015/speakers/
No comments:
Post a Comment