Monday, 22 July 2013


Part II Cystic Borrelia and Related Topics Including Round Body 

Infections of the brain.

Dr Alan MacDonald

Published on Jul 21, 2013

Cystic Borrelia are under appreciated in borrelia biology. This Lecture discusses the formation of Cystic Borrelia, and the Pathological effects in the human body which are
associated with Cystic borrelia, Especially in the Brain. Congential hydrocephalus caused by Gestational borreliosis [ 3cases in world literature ] are reviewed in Detail.
Discussion of the possibility of motility in Cystic borrelia is correlated with Electron Microscopyof borrelia Cystic forms. The String of Pearls form of borrelia is illustrated and the identification of Borrelia String of Pearls forms in human blood by Profesor Morten Laane is illustrated. Round bodies associated with various Nerodegenerative
Disorders in the Human [ ALS, Parkinson's, Cortical Lewy body Dementia. CorticoBasal Degeneration, Alzheimer's disease, FrontoTemporal Dementia] are correlated with parallel observations of Round Body Borrelia Invading Human Brain neurons in a case of Alzheimer's disease. A New paradigm of Round body Neuropathology is suggested for further Study as evidence of Invasive Cystic borrelia microbes. This Paradigm would shift the classification of Neurodegenerative disorders containing Round Intra-neuronal bodies from Idiopathic in Cause to Infectious Diseases of the Human Brain.
Alan B. MacDonald MD July 21,2013
forms in the Human Brain.

Thank you Doctor MacDonald for speaking in Plain English for those of us without a scientific background to understand better.


  1. This Lecture covers Cystic Borrelia
    and highlights the amazing research of Professor Laane with his proof the Cystic Borrelia exist in the circulating blood of some Chronic Borreliosis[Lyme borreliosis] patients.
    The String of Pearls breaks off from the parent Cystic form and also circulates in the blood. This form has never been previously documented in human blood as a circulating parasite.
    It is amazing to see the large number of entirely legitimate Borrelia forms in human blood in those patients with chronic infection.
    I predict that the microscope will be a more important tool for establishing a diagnosis of chronic Borrelia infection. with use of the lessons from Dr Laane, antibody testing will be replaced by direct detection of the Infection
    by means of blood examination, just as we detect malaria y blood examination, and other parasitic diseases by direct blood examination
    [chagas disease, sleeping sickness, leismaniasis
    and many others]
    The expert in Microscopy, Dr Laane, will teach the next generation of Hospital Pathologists in the proper diagnosis of Borrelia
    infections and of all of the Co-infections such as Babesiosis, Bartonellosis, Ehrlichiosis, Anaplasmosis, and others too. The Miyamotoi type of borrelia infection absolutely must now be diagnosed by direct microscopic examination
    because there is a present NO ANTIBODY TEST for it.
    All good wishes,
    Alan B. MacDonald, MD FCCAP FASCP
    July 24,2013

    1. Thank you Dr MacDonald for this further enlightening information - Professor Laane's microscopy work on Borrelia is indeed fascinating.

  2. This link takes you to an interesting video from Professor Morton Laane (as mentioned in Dr MacDonald's comment above)

  3. Revealing the bacteria
    "Using our method, the Borrelia bacteria in the red blood cells stand out clearly after one to two days at room temperature. We manage to make the bacteria visible without using staining (which can only be used on dead preparations). Keeping the bacteria alive allows us to monitor the bacteria through the microscope.
    The researchers add a dilute saline solution to the blood preparation. The blood cell then swells up and most of the blood plasma breaks up and disappears.
    "The swollen red blood cells become clearly visible. The images are sharper and clearer than those produced by other methods we know of, and they often show incredible details. We can observe how the bacteria emerge from the blood cells. Not all of the structures seen when the blood cells expel material are classically shaped Borrelia bacteria. Visualization of various Borrelia life stages can be enhanced by adjusting the concentration of the salt solution to give more detail.
    A common conception is that Borrelia bacteria in human blood have a spiral or zig-zag shape. However, the absence of such shapes in the blood does not exclude the presence of the bacteria. The researchers see examples of the bacteria straightening out after 24 hours, or they may exist as tiny structures with simple geometrical shapes, or form round structures (the aforementioned cyst stage).
    "Our experiments show that virtually all the bacteria change into the cystic form in the course of just one hour. We can then expose them to almost any antibiotic medication, but nothing destroy these.
    It is well known that these bacteria migrate and thrive in parts of the body with little oxygen, such as joint tissue. They lie there and wait for the host's health to deteriorate. Bacteria constantly leak out into the bloodstream. The patient is given antibiotics, which destroy the bacteria that leak out, the immune system recovers and the treatment stops. But the source is still in the body.

    Read more at:

    Fascinating work I wonder if that is why my RBC MIC is high ( usual suspects have been excluded)

  4. Video of Borrelia in the blood and what looks like borrelia from red blood cells

  5. Prof Morton Laane paper go to the bottom of this link for access to the full paper