Is your pain influenced by hormonal cycle ? ( worse flairs before, during or after cycle) - sorry to the men
Is your pain resilient to
standard treatment modifiers (NSAIDS, SSRI's, Neuroleptic mediators, Narcotics)?
Does antibiotic use increase or decrease pain (ie. Jarisch-Herxheimer reaction) given for such as sinus or UTI infections ?
Is you pain associated with multi-systemic symptoms?
Then you are probably looking at a Muti-Systemic Infectious Disease Syndrome - MSIDS
Watch this presentation by a leading doctor in this field Richard I. Horowitz, MD at a hearing
NB. RA and Lupus Rheumatoid factor correlates with antibody titres against Borrelia - Lyme Disease, something most Rheumatologist don't yet recognise.
In an earlier presentation By Dr Horowitz at the 2010 London ILADS conference DVD available through Lyme disease Action charity Dr Horowitz mentions that Plaquenil plus Minocycline often used in treatment for RA patients as a disease modifier regime - actually begs the question are they treating an underlying infection perhaps Lyme Disease and Mycoplasma.
I posted links to this hearing previously, Dr Horowitz presents in Part 1 here