BORRELIA LYME DISEASE AND CHRONIC DISEASES - LIFTING THE VEIL III -

Lifting the Veil III conference http://www.aonm.org/ 

A few notes from the conference, a video will be available from the AONM website in a couple of weeks.

Dr. Judy Mikovits Keynote Speech: The Terrain IS Everything! Lessons Learned from Four Decades of Immune Therapy.

Taking Mystic and misconceptions away from chronic diseases.
Many patterns of receptors on cells which bacteria can affect.
Plasticity in Immune response not one thing and one end result, it is a gradient and a tipping point.
How Borrelia affects immune system.
We are not thinking of vaccines as immune modulators, we are just thinking of them as disease control.
Advances in technologies reveal unintended consequences of current vaccine strategy.
Infants  can't develop immune responses but may develop an immune deficiency until 3 years old.
Recommended reading http://www.amazon.com/Immune-System-Developing-Brain-Colloquium/dp/1615043519
Disease engines - sub clinical, microbial infection, oxidative stress, inflammation.
Conclusion
Chronic neuro diseases emerging in the last 4 decades as Acquired Immune Deficiencies.
Utilizing advances in technology to drive paradigm shifts in understanding of basic biology affords incredible opportunity to end suffering and restore quality of lives to millions worldwide.

Dr. Armin Schwarzbach Chronic Infections ­ Transmission within Families and the Consequences 
Dr Mikovits introduced Dr Schwarzbach saying he had diagnosed over 20,000 Lyme Disease cases.
Transmission
Pathogen - infection- disease
2015 study - Germany Borrelia found in mosquitoes, also larva affected showing transmission.
Earlier studies found Borrelia in Horse flies.
1992 Deer Fly infected with Borrelia.
2015 Borrelia Miyamotoi could be transmitted by blood transfusion.
2014 Stricker study re sexual transmission may suggest yes but need more studies to be accepted.
2001 Dr MacDonald published In utero but there needs to be more data supporting this.
In utero transmission in dogs.
1995 Fetal outcome in murine Lyme Disease.
1991 Relative infective of Borrelia Burgdorferi in Lewis rats.
Some co infections
Bartonella - Fleas, Mosquitoes, sand flies
Babesia - blood transfusions
Rickettsia - very dangerous for heart
Coxiella Burnetii (Q fever) usually by inhalation also by tick bites.
Opportunistic infections:-
Cpn
Mycoplasma
Herpes groups 1-6
Yersinia
Coxsackie virus
E.B.V
Cytomegalovirus
HHV6
Are we too focused on Borrelia?
Are there other consequences of other infections within families to re infect?

Dr. Marjo Valonen Case Reports: Herbal and Nutritional Treatment Protocols in Lyme and Co­Infections
Treating herbals mainly in her clinic in Finland.
Used to use antibiotics and still does but more and more using herbals.
Describes it as a war fighting microbes.
Big part of our work is to rebuild
Discusses Horowitz MSIDS concept and likes to follow this.
Supplement plan includes
High quality nutrition
Vitamin C natural forms or liposomal
Fish oils
Magnesium
Discussed case studies. 
Uses Cowden plus other herbals repeating testing for Borrelia WB, Elispot, Cpn and other co infections.
Recommends TICKPLEX a new test http://www.tickplex.com/
link to the clinic Dr Valonen runs  http://www.astris.fi/laakarit/ 

Professor Malcolm Hooper 3 T(ear)s for PACE: Travesty of Science, Tragedy for Patients, Tantamount to Fraud 
Travesty of science
Tragedy for patients
Tantamount to fraud
Starts with Prof Wessley with Functional Somatic Syndrome in 1999
Abhors - Non specific symptoms, as if you look you can find symptoms.
Response is CBT and GET!
People are so fixated they have stopped thinking.
Discusses his involvement with GWvets, ME CFS Fibromyalgia, and Multiple Chemical Sensitivity which are all syndromes of uncertain origin, another word Neurasthenic or M.U.S multiple unexplained symptoms. These are words of ignorance!
Organic phosphate poisoning - farmers
Aerotoxic syndrome - TCPs jet engine oils - pilots and cabin staff worst affected ( described by doctors as hyperventilation!)
Gulf War vets 25-30% are sick - used pesticides malathion etc, nerve gas sarin, given Pyridostigmine bromide - triple whammies.
Then given vaccines and even non deployed got vaccines and they were also affected.
Government lies.
Response is PACE designed to validate CBT and GET
There was no objective measurement,  no blinding a sine quo non for subject data. Original entry requirement was changed and manipulated. Moving goal posts.
D Tuller has done lots of papers regarding PACE Trial by Error was published in three parts in Virology blog -   http://www.virology.ws/2015/10/21/trial-by-error-i/
NICE guidelines on ME are unfit for purpose

Dr. Joseph Jemsek Applying Common Sense and Lessons Learned in Lyme Borreliosis Complex
'Everything I have learned I have learned from patients'
Chronic relapsing or otherwise 'unexplained' encephalopathy ---arthritic and list of symptoms 
Complex
Jill Livengood 10 years ago found in all neuronal cells tested observed Borrelia Burgdorferi in all cells. - http://www.ncbi.nlm.nih.gov/pubmed/17045505

Invasion of human neuronal and glial cells by an infectious strain of Borrelia burgdorferi.

70+ papers on persistence in human and animal models

Problem areas not enough treatment for Babesia and Biofilms.

Have to kill what comes out of bio films.

Chronic oxidative stress - chronic inflammation

Discussed limbic system with diagram

2003 Salazar et al found memory CD27 cells in Erythema migrans rashes indicating EM was not first exposure to the organism.

http://www.ncbi.nlm.nih.gov/pubmed/12928420

Listed various supportive treatments including Kefir, green tea, Yoghurt, coconut oil

Moles commonly found

Neurofibromas growth on nerves

Bone growth often associated with Bartonella

Dr. Alan MacDonald (via live video link from Florida) Chronic Borreliosis and Chronic Seronegative Lyme Disease ­ DNA Probes Solve a Diagnostic Conundrum
Dr Alan MacDonald's recent work finding Nematode worms in Multiple sclerosis MS patients spinal fluid and also finding Borrelia ( Lyme Disease) in the worms.

London Lecture May 15 2016 from Alan MacDonald on Vimeo.


A really excellent conference. Apologies for any mistakes I may have made in copying up my notes. 

I hope it encourages you to get the original presentations available shortly from AONM website 
http://www.aonm.org/


Presentations now available 
http://aonm.org.uk/ltv%20III

Lifting the Veil I
 http://lookingatlyme.blogspot.co.uk/2015/03/dr-judy-mikovits-infectious-pathogens.html

Lifting the Veil II
 http://lookingatlyme.blogspot.co.uk/2015/11/chronic-illness-testing-infections.html

CHRONIC ILLNESS - TESTING - INFECTIONS - IMMUNE SUPPORT

                   Photo courtesy of Mark Christian

Lifting The Veil II  

at the Academy Of Nutritional Medicine on Sunday 15th November 

Just a brief summary of this excellent conference - the presentations will shortly be available on the AONM website http://www.aonm.org  and a DVD will eventually be available from that website.

Professor B.K. Puri

http://breakspearmedical.com/

Discussed ECG 

History - 1887 Augustus Waller first discovered the use of ECG at St Marys London carrying out the first ECG on a dog and then moved to humans. He also mapped the electrical field around the heart and produced a heart graph using PQRST.

Long QT Syndrome is found in 1 in 2500 of the population and can be hereditary.

Can cause rapid heart beat, seizures, respiratory arrest.

All SSRI's ( Selective serotonin reuptake inhibitors) can cause LQT interval.

All anti psychotic medication can cause LQT interval

Erythromycin orally can cause LQT interval a 300% higher risk of death from this than in patients taking Amoxycillin.

Environmental exposure to certain metals eg lead can increase risk of LQT interval.

Discussed Atrioventricular block
He discussed a paper in 1990 written by Dr Allen Steere on a case of AV block leading to death after an appendectomy - which said that Lyme Carditis must be considered especially in young patients with AV block.

Discussed a further cardiac study didn't catch the authors name 20% had right induction delay but after 2 weeks treatment ECG returned to normal.

Dr Monro

http://breakspearmedical.com/

Discussed at length food intolerances, allergies and sensitivities under various headings Rationale, Investigations and treatment.

Harboring toxins may need detox procedures

Can't ignore the fact a person who has Lyme had intolerances before infection.

Can have homeostasis working when healthy but can be dragged down by infection.

Need to lift whole thing up simultaneously to lift patient up.

Food sensitivities - historically we all know about this - various intolerances 

Celiac has been associated with schizophrenia and a study found they improved when they couldn't get wheat during the war.

Studies have been done on wheat free and milk free.

In Celiac and in autism cases wheat free diet gave some improvements. 

The Breakspear clinic hold a massive collection of books and papers ( not all found on Pub med)
She recommended a book Not all in the Mind by Richard Mackarness

 http://www.amazon.co.uk/Not-All-Mind-Richard-Mackarness/dp/0330245929

Anaphylactic shock was first described in 1901 and is an affect of the Autonomic nervous system. It was recognised in 1940 as a histamine release.

Discussed oral tolerances, no mast cells under the tongue so can use that to introduce oral tolerances.

Low dose immunotherapy.

Started with hay fever introduced weaker dilutions and can be used as a vaccine.

discussed two pathways ANS and Lymphocytes.

Emphasized people with chronic infections have allergies and these must be addressed.
Quoted 1/3 of the population had migraine. 1/3 of the population had IBS

Dr Klinghardt 

http://www.klinghardtacademy.com/

Started by giving a tribute to the work of Dr Jean Monro 

He did his thesis on the Autonomic nervous system (ANS) and the immune system, his colleagues thought ANS outdated - it was the beginning of a career in ANS. In Germany growing up he became interested in homeopathy, acupuncture and ANS.

Moving to the US different legal systems only allowed to use his hands so adopted his methodology.

Talks about 3 components

1. Genetic and epigenetic

2. Environmental challenge

3. The immune response to toxins, microbes, parasites.

"The response of the host makes the disease" Lewis Thomas MD -NEJM 1972.

Treating chronic Illnesss he uses 4 principles

1. Basic physiology - exercise, diet, trauma, work and transgenerational physiologies, hormones, vitamins, osteopathy,EMR protection

2. Decreasing toxic body burden- metals,chemicals & Biotoxins from extra and intra cellular matrix, EMR protection.

3. Immune Modulation- up regulating blocked or underactive immune function & down regulating hyperactive ones 

4. Decreasing microbial burden  diagnosisn & treating parasites, mould, viruses,( HSV, EBV etc) bacteria eg Borrelia, bartonella, protozone ( Babesia, toxoplasmosa, omeba)

Stressed the importance of paleo diet and benefits of Japaneese knotweed for long term treatment to keep Lyme at bay. also a need for using antivirals.

Discussed 

1. Toxicity

2. Unresolved psycho evolutionary & trans generation issues

3. EMR microwave, electricity & magnetic fields

4. Infections

5. PANDAS & PANS

6. HPU (HemoPyrrollactanUria)

7. CCSVI

8. Dental issues

9. ? Brain waves

10.Decreased regulatory neuropeptides & hormonal deficiencies

Says he believes it is a mistake to try to fix hormonal issues ie in Babesia - hormones can make more toxic and need to come later in treatment.

Illness & Epigenetics

psychological and physical trauma

In animal models epimutations followed 7 generations generally led to study families dying out.

We are now third generation exposed to microwave and glyphosate 

Epimutations 1000x more significant than genetic mutations.

We do not have epigenetic testing yet.

Need to look at ways to help methylation.

Chlorella and chelation for heavy metals.

Aluminium particularly related with neuro toxins & pro inflammatory but no testing.

Tests that can help are 

Low WBC

Elevated MCV

elevated fasting blood sugar 90-110

low alkaline phosphate

moderately elevated LDC

Low urine specific gravity

are often indicated in the sickest patients.

Artimisin helpful and mentions a Lyme cocktail found on his website (link above)

John Caudwell

https://www.facebook.com/johndcaudwell/?fref=ts

Spoke briefly about the journey he and his family had been on for the last 6 weeks. He has quickly recognised the lack of help from NHS and acknowledged how caring the lyme community was, he expects to interview for Chief Executive next week for a new charity for Lyme whose aim will be to get NHS to take responsibility for this patient group. He has been moved by the numbers of tragic stories. Much of what he said can be read on his Facebook page.

Dr Sarah Myhill

http://www.doctormyhill.co.uk/

Sometimes I am ashamed to be a doctor - the biggest problem is the medical profession. Driven by pharmaceutical drugs to treat symptoms- it is important to ask what is the mechanisms going wrong.

Fatigue we all have, energy demand outstrips energy delivery 

Chronic fatigue - many have immunological symptoms.

ME also have inflammatory symptoms.

In CFS

1. Very poor stamina

2. delayed fatigue

are only two symptoms looked for.

Energy loss

Muscles - No stamina, weakness

brain - Foggy brain, poor energy delivered to brain. Having low mood or depression may be way of conserving energy such as in low seasonal defective disorder.

stress

eye - inability to read watch TV, photophobia- light intolerances

ear- noise intolerances

Immune system - activate immune system, such as in flu you

Intolerance heat & cold - requires energy. 

Gut & Liver- eating toxic food puts greater demands on liver

Hormone synthesis - likely to be slow

Cardiac symptoms - extremely common Heart symptoms compound all other symptoms. POTS - autonomic problem but can be a symptom of lack of energy to the heart.

Symptoms of inflammation can be localised or generalised. She draws a great analogy to a car engine  in respect of Mitachondria, diet, gut, lungs,heart circulation,Thyroid,Adrenal.

Need to pace energy but also mental energy. But refers to PACE as an oxymoron because if you get better with PACE therapy you do not have CFS.

Discusses various books she has written highlights importance of diet.

Modern diseases fueled by carbohydrate & sugar diets. Most important to follow stone age diet.

sleep - imperative 

Circadian rhythm

Sunshine & light vit D anti inflammatory, 

Avoid infections- acute infection is one thing but can switch on a chronic immune reaction.

(In generally ie flu or a cold she believes that symptoms of acute infection should not be suppressed by drugs, need to go to bed and rest, need to let immune system work).

Discussed tools to treat poor energy levels included CoQ10,Vit B3, magnesium, D ribose, vit B12 She says even if you can't get testing done this selection is very helpful and unlikely to do any harm.

Major source of toxins from fermenting gut. Alcohol intolerance is recognsied in ME patients uniformly.

Discussed thyroid function indicating problems with testing and the need to go on clinical symptoms. TSH is set high in UK and everyone has their own individual range.

Adrenal function - stress - mitochondria output

Detoxify- saunas can get rid of toxic load but not heavy metals.

Dr Schwartzbach 

http://www.arminlabs.com

Dr Schwardtzbach has tested more than 1000 samples from the UK and astounded how many tests are positive.

He gave an overview of infections and viruses that it is important to consider testing for in chronic diseases such as ME, MS, Fibromyalgia, RA,Alzheimers, Parkinsons, Autism.

Quoted that 50% of people in Sweden have Lyme Disease.  

It is a big problem to diagnose parasites only one lab that does that which is Fry labs in US.

Says CD57+ NK cells very important.

Learn from TB that it is reaction on T cells not B cells.

Only study on CD57 was one done by Stricker.

CD57 can be low in Chlamydia & Mycoplasma - need studies.

Elispot is test for T cells

very established, actual activity of T cells fighting against actual infections

sensitivity -84%

specificity -94%

Most doctors say it is unspecific everybody has it - but there is no argument to say this.

Patients not positive but have low CD57 if they are treated they improve and CD57 raises.

It uses the same bands that are used in the Western Blot.

antigen from B31 strain, OspA, Sensu stricto, Afzelii,garinii, + OspC native + DbpA? recombinant

The tests are CE certified - he does not produce the test he just uses them.

Tests support a clinical diagnosis

Doctors need to learn to make a clinical diagnosis it is not easy and no time to asses it needs specialists.

Immunoblot time will end in a year of two not because there is no Lyme.

Denmark don't use the Western blot they only use the ELISA based on only one study which was done by the person who owns the lab that does the tests.

Spot Technique

MicroArray

Seraspot

can quantify 60% in Chronic with 99% specificity

20%-30% Lyme positive in Autism - Bransfield

90% CFS Lyme positive

2014 - Pure Lyme dementia exists& has good outcomes in treated patients. Dementia patients should be tested.

Seems Koala bears can be treated for Chlamydia but not so humans.

Common symptoms of Chlamydia are cough, sinusitis and can cause all symptoms and illness as Lyme Borreliosis

Garth Nicolson - Mycoplasma

Can keep ticks in polythene bag in freezer/fridge? for testing

Elhrickia

Bartonella was found in 40% of ticks in Germany.

Showed a slide of Bartonella striae which are common.

Babesia very Important for blood transfusions services.

Ricketsia

EBV not found in ticks yet

Cytomegalovirus (CMV)

Herpes Simplex Virus linked with MS co factor CFS, Fibromyalgia

Coxsackie Virus nearly everyone in UK has IgA for CV

Most Fibromyalgia patients are Lyme positive.

Lyme found in Otzi died 50 million years ago.

oldest tick with Lyme found from 40 million years ago

Important to look for co infections too.

Autism 50% have chlamydia as well as 10-20% Borrelia but need to look for other infections

To treat viruses - barbour, artemisin, samento very difficult to eliminate - blocking mitochondria.

Dr Newton

https://uk.linkedin.com/in/chris-newton-813ab229

Gave a brief update of a result of a visit to Porton Down in June. There will be a new initiative to try and raise funds for work on a UK direct testing method to find Borrelia this will be launched in a few days 

FIGHT LYME NOW 

Dr Alan MacDonald

https://www.gofundme.com/z3v2a2k

presentation by Vimeo with question and answers by skype.

Review of Infectious Borrelia species Chronic Brain Infections and the Development of Alzheimer's Disease from Alan MacDonald on Vimeo.